Predictive biology for health: a cross-section of socio-economic and scientific issues in humans, animals and plants.

Summary Predictive medicine is renewing therapeutic practices. It is being deployed, in particular, thanks to the massive acquisition of biological, behavioral and sociological data, making it possible to establish predictions on the basis of genetic and environmental information. These predictive approaches for health are also at the heart of current research in animals and plants, with the common objective of promoting resistance to pathogens and environmental stresses while reducing the use of antibiotics, phytopharmaceuticals, fertilizers and water, in order to promote the ecological transition in agriculture. In a scientific and socio-economic context where health research is still largely conducted in silos, there is an emerging desire to break down the barriers between different themes. The One Health initiative, which aims to combine research in human health and animal health, in relation to the environment, is emblematic of this approach. The objectives of the seminar were to exchange information between biologists, lawyers, ethicists and economists on the approaches and new knowledge that contribute to the development of strategies for prediction, diagnosis, prevention and decision-making. The ambition of the seminar was to integrate into the discussion the issues and research in animal and plant health, in a shared perspective of global health. The seminar was organized within the framework of the PREDICT strategic research initiative, supported by the Life Sciences Department and the Maison des Sciences de l'Homme Paris-Saclay. PREDICT is part of a long-term prospective vision on predictive approaches for health and offers an original space for reflection on ethics, law and economics between the communities of breeding, plant production and medicine.